SCHEMBL727469

SCHEMBL727469

CCCCSc1ccc(C(=O)C(C)(C)N2CCOCC2)cc1

nearest known ligand 0.66

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.66
ALDH1A1 P00352 3/20 0.66
MAPK1 P28482 2/20 0.66
TSHR P16473 1/20 0.66
HRH3 Q9Y5N1 1/20 0.48
KDM4E B2RXH2 1/20 0.44
THRB P10828 6/20 0.43
POLB P06746 2/20 0.42
LMNA P02545 2/20 0.41
THRA P10827 2/20 0.41
RAB9A P51151 2/20 0.40
MAPT P10636 2/20 0.40
TP53 P04637 1/20 0.40
FKBP1A P62942 1/20 0.40
NPC1 O15118 1/20 0.40
USP2 O75604 1/20 0.40
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10649119 0.96 SMN1; SMN2 (0.64) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL9679909 0.95 SMN1; SMN2 (0.63) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10885407 0.95 SMN1; SMN2 (0.63) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL278825 0.94 SMN1; SMN2 (0.71) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL17324198 0.92 SMN1; SMN2 (0.69) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10883782 0.91 SMN1; SMN2 (0.74) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL5822546 0.89 SMN1; SMN2 (0.64) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL8167452 0.88 SMN1; SMN2 (0.63) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL16788934 0.88 SMN1; SMN2 (0.57) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3
SCHEMBL10887683 0.87 SMN1; SMN2 (0.69) SMN1; SMN2ALDH1A1MAPK1TSHRHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230104836-A1 TRANSFER FILM AND METHOD FOR PRODUCING LAMINATE FUJIFILM CORPORATION (JP) 2023-04-06 US disclosed
EP-2585431-B1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2017-09-06 EP disclosed
EP-2585431-B1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2017-09-06 EP disclosed
US-9657435-B2 Metal free bleaching composition BASF SE (DE) 2017-05-23 US disclosed
US-9657435-B2 Metal free bleaching composition BASF SE (DE) 2017-05-23 US disclosed
US-9657435-B2 Metal free bleaching composition BASF SE (DE) 2017-05-23 US disclosed
US-20130117941-A1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2013-05-16 US disclosed
US-20130117941-A1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2013-05-16 US disclosed
US-20130117941-A1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2013-05-16 US disclosed
EP-2585431-A1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2013-05-01 EP disclosed
WO-2012000846-A1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2012-01-05 WO disclosed
WO-2012000846-A1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2012-01-05 WO disclosed
US-5145885-A Morpholine compound, binders CIBA-GEIGY CORPORATION (US) 1992-09-08 US disclosed
US-4992547-A Aminoaryl ketone photoinitiators CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed
US-4582862-A QUICK-SETTING PRINTING INKS BASED ON ACRYLATED RESINS CIBA-GEIGY CORPORATION (US) 1986-04-15 US disclosed