Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.62 |
| ▸ | PIM1 | P11309 | 1/20 | 0.62 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.62 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.54 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.52 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674576 | 1.00 | KDM4E (0.65) | KDM4EKMT2ACHEK1PIM1MAPK8 | |
| SCHEMBL6677116 | 0.92 | CHEK1 (0.70) | KDM4EKMT2ACHEK1PIM1MAPK8 | |
| SCHEMBL6675681 | 0.92 | CHEK1 (0.70) | KDM4EKMT2ACHEK1PIM1MAPK8 | |
| SCHEMBL6676947 | 0.87 | KDM4E (0.60) | KDM4EKMT2AMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL6678169 | 0.87 | KDM4E (0.60) | KDM4EKMT2AMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL7643669 | 0.84 | MEN1 (0.60) | KDM4EKMT2AMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL7643672 | 0.84 | MEN1 (0.60) | KDM4EKMT2AMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL266327 | 0.82 | CHEK1 (0.80) | KDM4EKMT2ACHEK1PIM1MAPK8 | |
| SCHEMBL22887373 | 0.82 | CYP1A2 (0.63) | KDM4EKMT2AMAPK1HSD17B10ALDH1A1 | |
| SCHEMBL22887376 | 0.82 | CYP1A2 (0.63) | KDM4EKMT2AMAPK1HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | claimed |
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | TELIK, INC. | 2002-03-14 | — | — | US | claimed |
| EP-1289936-B1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK INC (US) | 2004-10-20 | — | — | EP | disclosed |
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | TELIK, INC. | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | SLC2A1, SLC2A8, SLC2A2 | KDM4E 3079/4885KMT2A 3788/4885CHEK1 1685/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.