Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | SNCA | P37840 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678169 | 1.00 | KDM4E (0.60) | KDM4EHSD17B10MAPK1SNCAALDH1A1 | |
| SCHEMBL7643672 | 0.90 | MEN1 (0.60) | KDM4EHSD17B10MAPK1SNCAALDH1A1 | |
| SCHEMBL7643669 | 0.90 | MEN1 (0.60) | KDM4EHSD17B10MAPK1SNCAALDH1A1 | |
| SCHEMBL2272655 | 0.90 | KDM4E (0.60) | KDM4EHSD17B10MAPK1SNCAALDH1A1 | |
| SCHEMBL2272660 | 0.90 | KDM4E (0.60) | KDM4EHSD17B10MAPK1SNCAALDH1A1 | |
| SCHEMBL6674568 | 0.87 | KDM4E (0.65) | KDM4EHSD17B10MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL6674576 | 0.87 | KDM4E (0.65) | KDM4EHSD17B10MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL7524206 | 0.86 | PTGS2 (0.52) | KDM4EHSD17B10SNCAALDH1A1CYP1A2 | |
| SCHEMBL7524215 | 0.86 | PTGS2 (0.52) | KDM4EHSD17B10SNCAALDH1A1CYP1A2 | |
| SCHEMBL6673496 | 0.86 | MEN1 (0.62) | SNCAALDH1A1MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289936-B1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK INC (US) | 2004-10-20 | — | — | EP | claimed |
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | claimed |
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | TELIK, INC. | 2002-03-14 | — | — | US | claimed |
| EP-1289936-B1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK INC (US) | 2004-10-20 | — | — | EP | disclosed |
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | TELIK, INC. | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | SLC2A1, SLC2A8, SLC2A2 | KDM4E 3079/4885HSD17B10 1302/4885MAPK1 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.