Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15825041 | 0.85 | NQO2 (0.56) | NQO2CYP19A1KDM4EMAPTMEN1 | |
| SCHEMBL7026646 | 0.81 | CASP6 (0.41) | CYP19A1KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL6671371 | 0.81 | NQO2 (0.56) | NQO2CYP19A1KDM4EMAPTMEN1 | |
| SCHEMBL6672275 | 0.79 | CYP19A1 (0.46) | NQO2CYP19A1KDM4EMAPTMEN1 | |
| SCHEMBL6674677 | 0.76 | NQO2 (0.54) | NQO2CYP19A1KDM4EMAPTMEN1 | |
| SCHEMBL24815907 | 0.75 | ADRA2A (0.47) | CYP19A1MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL21230826 | 0.75 | CYP19A1 (0.45) | NQO2CYP19A1KDM4EMAPTMEN1 | |
| SCHEMBL17883981 | 0.75 | CYP19A1 (0.45) | NQO2CYP19A1KDM4EMAPTMEN1 | |
| SCHEMBL6668282 | 0.73 | KDM4E (0.40) | NQO2CYP19A1KDM4EMAPTALDH1A1 | |
| SCHEMBL27295494 | 0.71 | ALDH1A1 (0.40) | NQO2CYP19A1KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4617262-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Kyoto University (JP) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024101336-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | 国立大学法人京都大学 | 2024-05-16 | — | — | WO | disclosed |
| WO-2024101336-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | 国立大学法人京都大学 | 2024-05-16 | — | — | WO | disclosed |
| WO-2023143135-A1 | QUINAZOLINE DERIVATIVE AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2023-08-03 | — | — | WO | disclosed |
| CN-116514728-A | Quinazoline derivative and application thereof | 赛诺哈勃药业（成都）有限公司 | 2023-08-01 | — | — | CN | disclosed |