Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 2/20 | 0.55 |
| ▸ | EBP | Q15125 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.52 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.52 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.46 |
| ▸ | GLB1 | P16278 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21210655 | 1.00 | GUSB (0.55) | GUSBEBPSIGMAR1GNAI3GNAO1 | |
| SCHEMBL6674218 | 1.00 | GUSB (0.55) | GUSBEBPSIGMAR1GNAI3GNAO1 | |
| SCHEMBL6674222 | 1.00 | GUSB (0.55) | GUSBEBPSIGMAR1GNAI3GNAO1 | |
| SCHEMBL23765241 | 0.96 | GUSB (0.55) | GUSBEBPSIGMAR1GNAI3GNAO1 | |
| SCHEMBL23435369 | 0.89 | GUSB (0.55) | GUSBEBPSIGMAR1GNAI3GNAO1 | |
| SCHEMBL14877527 | 0.89 | GNAI3 (0.64) | GNAI3GNAO1GNAI1BCHE | |
| SCHEMBL18698673 | 0.87 | BCHE (0.55) | GNAI3GNAO1GNAI1BCHE | |
| SCHEMBL20858275 | 0.83 | GUSB (0.59) | GUSBEBPSIGMAR1GNAI3GNAO1 | |
| SCHEMBL20858345 | 0.83 | GUSB (0.59) | GUSBEBPSIGMAR1GNAI3GNAO1 | |
| SCHEMBL19275301 | 0.83 | GUSB (0.59) | GUSBEBPSIGMAR1GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0899259-B1 | Process for the preparation of cis-hexahydroisoindolines | YUKI GOSEI YAKUHIN KOGYO KK (JP) | 2004-10-13 | — | — | EP | disclosed |
| US-5932744-A | Process for the preparation of cis-hexahydroisoindoline derivatives | YUKI GOSEI KOGYO CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0899259-A1 | Process for the preparation of cis-hexahydroisoindolines | YUKI GOSEI KOGYO CO., LTD. (JP) | 1999-03-03 | — | — | EP | disclosed |