Toyocamycin

Toyocamycin

SCHEMBL6674952

N#Cc1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12

nearest known ligand 0.80

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADK P55263 10/20 0.80
DOT1L Q8TEK3 5/20 0.80
PAX8 Q06710 2/20 0.67
NPC1 O15118 1/20 0.67
GALR3 O60755 1/20 0.67
S1PR4 O95977 1/20 0.67
ALDH1A1 P00352 1/20 0.67
MAPT P10636 1/20 0.67
S1PR1 P21453 1/20 0.67
HTT P42858 1/20 0.67
RAB9A P51151 1/20 0.67
PRMT5 O14744 1/20 0.65
PRMT3 O60678 1/20 0.65
DNMT1 P26358 1/20 0.65
EHMT2 Q96KQ7 1/20 0.65
HIF1A Q16665 1/20 0.65
CDK5 Q00535 1/20 0.64
CDK5R1 Q15078 1/20 0.64
DPP4 P27487 1/20 0.58
MEN1 O00255 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toyocamycin SCHEMBL2786616 1.00 ADK (0.80) ADKDOT1LPAX8NPC1GALR3
Toyocamycin SCHEMBL17395285 1.00 ADK (0.80) ADKDOT1LPAX8NPC1GALR3
Toyocamycin SCHEMBL29363964 1.00 ADK (0.80) ADKDOT1LPAX8NPC1GALR3
Toyocamycin SCHEMBL13064386 1.00 ADK (0.80) ADKDOT1LPAX8NPC1GALR3
Toyocamycin SCHEMBL20438004 1.00 ADK (0.80) ADKDOT1LPAX8NPC1GALR3
Toyocamycin SCHEMBL14642992 1.00 ADK (0.80) ADKDOT1LPAX8NPC1GALR3
Toyocamycin SCHEMBL14642728 1.00 ADK (0.80) ADKDOT1LPAX8NPC1GALR3
Toyocamycin SCHEMBL2786620 1.00 ADK (0.80) ADKDOT1LPAX8NPC1GALR3
Toyocamycin SCHEMBL336095 1.00 ADK (0.80) ADKDOT1LPAX8NPC1GALR3
SCHEMBL16978197 0.89 ADK (1.00) ADKDOT1LPAX8NPC1GALR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026086871-A1 ANTI-AGEING COMPOUNDS, USES THEREFOR, METHOD FOR IDENTIFYING, AND COMPOSITIONS CONTAINING Centre for Translational Stem Cell Biology Limited (CN) 2026-04-30 WO disclosed
US-20190038597-A1 PREVENTION OF VASCULAR AND CARDIAC FIBROSIS VIA IRE1ALPHA INHIBITION MCMASTER UNIVERSITY (CA) 2019-02-07 US disclosed
WO-2015120314-A1 POLYPEPTIDES HAVING NITRILE HYDRATASE ACTIVITY AND POLYNUCLEOTIDES ENCODING THE SAME ARIZONA BOARD OF REGENTS FOR THE UNIVERSITY OF ARIZONA (US) 2015-08-13 WO disclosed
WO-2004037159-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING FAT METABOLISM OBETHERAPY BIOTECHNOLOGY (FR) 2004-05-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190038597-A1 PREVENTION OF VASCULAR AND CARDIAC FIBROSIS VIA IRE1ALPHA INHIBITION XBP1, ERN1, ERN2 ADK 1657/4885DOT1L 3893/4885PAX8 2426/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.