Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 11/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TNF | P01375 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | IL6 | P05231 | 1/20 | 0.54 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.54 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.54 |
| ▸ | GLUL | P15104 | 1/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.54 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4091523 | 0.96 | PGR (0.61) | PGRHIF1ALMNANR3C1CYP3A4 | |
| SCHEMBL13692224 | 0.91 | PGR (0.63) | PGRHIF1ALMNANR3C1CYP3A4 | |
| SCHEMBL6678012 | 0.91 | HIF1A (0.57) | PGRHIF1ALMNANR3C1CYP3A4 | |
| SCHEMBL4097537 | 0.89 | PGR (0.69) | PGRHIF1ALMNANR3C1CYP3A4 | |
| SCHEMBL4103929 | 0.89 | PGR (0.75) | PGRHIF1ALMNANR3C1CYP3A4 | |
| SCHEMBL13694233 | 0.88 | HIF1A (0.58) | PGRHIF1ALMNANR3C1CYP3A4 | |
| SCHEMBL13692244 | 0.88 | HIF1A (0.58) | PGRHIF1ALMNANR3C1CYP3A4 | |
| SCHEMBL4091992 | 0.88 | HIF1A (0.58) | PGRHIF1ALMNANR3C1CYP3A4 | |
| Hydrochloric Acid SCHEMBL5972770 | 0.87 | HIF1A (0.58) | PGRHIF1ALMNANR3C1CYP3A4 | |
| SCHEMBL13694190 | 0.87 | HIF1A (0.67) | PGRHIF1ALMNANR3C1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470150-A2 | CORTICOSTEROIDS NITRATE DERIVATIVES | Nicox S.A. (FR) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064443-A2 | NEW CORTICOSTEROIDS | NICOX S.A. (FR) | 2003-08-07 | — | — | WO | disclosed |