Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PARP1 | P09874 | 2/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7050989 | 0.85 | CYP1A2 (0.58) | CYP1A2LMNAAGTR1KDM4EHTT | |
| SCHEMBL7492316 | 0.85 | HTT (0.59) | CYP1A2LMNAKDM4EHTTMEN1 | |
| SCHEMBL11631740 | 0.84 | CYP1A2 (0.57) | CYP1A2LMNAAGTR1KDM4EMEN1 | |
| SCHEMBL30151910 | 0.82 | HTT (0.65) | CYP1A2LMNAKDM4EHTTMEN1 | |
| SCHEMBL7754052 | 0.81 | ABCB1 (0.69) | CYP1A2LMNAAGTR1KDM4EABCB1 | |
| SCHEMBL26326254 | 0.80 | CYP1A2 (0.81) | CYP1A2LMNAAGTR1KDM4EHTT | |
| SCHEMBL28229749 | 0.80 | HTT (0.58) | LMNAKDM4EHTTMEN1KMT2A | |
| SCHEMBL13763533 | 0.80 | HTT (0.71) | LMNAKDM4EHTTMEN1KMT2A | |
| SCHEMBL5692223 | 0.80 | IRAK4 (0.43) | CYP1A2LMNAAGTR1KDM4EHTT | |
| SCHEMBL4862369 | 0.79 | HTT (0.54) | CYP1A2LMNAKDM4EHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037159-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR MODULATING FAT METABOLISM | OBETHERAPY BIOTECHNOLOGY (FR) | 2004-05-06 | — | — | WO | disclosed |