Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12569696 | 0.88 | PRKCI (0.38) | GRM2PRKCINR1H2ACHESSTR4 | |
| SCHEMBL8169426 | 0.87 | RIPK1 (0.46) | RIPK1HTR2CSLC6A4HTR2APRKCI | |
| SCHEMBL6674369 | 0.87 | PRKCI (0.41) | GRM2HTR2CPRKCINR1H2ACHE | |
| SCHEMBL6682105 | 0.87 | PRKCI (0.37) | GRM2PRKCINR1H2ACHEAAK1 | |
| SCHEMBL6675964 | 0.86 | HTR2A (0.40) | GRM2HTR2CSLC6A4HTR2APRKCI | |
| SCHEMBL7246662 | 0.84 | GAA (0.36) | GRM2HTR2CSLC6A4HTR2APRKCI | |
| SCHEMBL6675380 | 0.83 | AAK1 (0.37) | GRM2PRKCINR1H2ACHEAAK1 | |
| SCHEMBL24891920 | 0.83 | GRM2 (0.36) | GRM2PRKCINR1H2ACHEAAK1 | |
| SCHEMBL30182580 | 0.83 | GRM2 (0.36) | GRM2PRKCINR1H2ACHEAAK1 | |
| SCHEMBL12547119 | 0.82 | GRM2 (0.34) | GRM2PRKCINR1H2ACHEAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6534546-B1 | Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |