Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.48 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15983852 | 0.82 | CTSK (0.50) | CTSKCTSSSYKATMIDO1 | |
| SCHEMBL16379594 | 0.82 | CTSK (0.50) | CTSKCTSSSYKATMIDO1 | |
| SCHEMBL6690446 | 0.82 | CTSK (0.48) | CTSKCTSSSYKATMIDO1 | |
| SCHEMBL15283622 | 0.81 | CTSK (0.55) | CTSKCTSSSYKATMCTSL | |
| SCHEMBL15979342 | 0.80 | SYK (0.48) | CTSKCTSSSYKATMIDO1 | |
| SCHEMBL2723123 | 0.80 | SYK (0.71) | CTSKCTSSSYKATMCTSL | |
| SCHEMBL2723119 | 0.80 | SYK (0.71) | CTSKCTSSSYKATMCTSL | |
| SCHEMBL1624911 | 0.79 | NPC1 (0.58) | CTSKCTSSSYKATM | |
| SCHEMBL7739354 | 0.79 | NPC1 (0.58) | CTSKCTSSSYKATM | |
| SCHEMBL350453 | 0.79 | NPC1 (0.58) | CTSKCTSSSYKATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| US-6534546-B1 | Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |