SCHEMBL6675822

SCHEMBL6675822

O=c1cc(C(F)(F)F)c2cc3c(cc2[nH]1)OCO3

nearest known ligand 0.63

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AR P10275 20/20 0.63
NR3C1 P04150 2/20 0.55
PGR P06401 2/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6308099 0.77 AR (0.90) ARNR3C1PGR
SCHEMBL3023968 0.77 AR (1.00) ARNR3C1PGR
SCHEMBL3005707 0.76 AR (1.00) ARNR3C1PGR
SCHEMBL3017710 0.74 AR (1.00) ARNR3C1PGR
SCHEMBL3019330 0.72 AR (0.75) ARNR3C1PGR
SCHEMBL3016771 0.72 AR (0.66) ARNR3C1PGR
SCHEMBL3012010 0.72 AR (1.00) ARNR3C1PGR
SCHEMBL3022968 0.72 AR (0.73) ARNR3C1PGR
SCHEMBL3013354 0.72 AR (1.00) ARNR3C1PGR
SCHEMBL5299756 0.72 AR (0.65) ARNR3C1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1181341-B1 LUMINESCENT 4-TRIFLUOROMETHYL-2-QUINOLONES WITH LONG-WAVE UV-ABSORPTION AND THE USE THEREOF URAY GEORG (AT) 2004-10-27 EP disclosed
US-6635759-B2 Used as luminescent marker for peptides, proteins, RNA and DNA, as complexing agent Uray, Georg (AT) 2003-10-21 US disclosed
US-20020058793-A1 Luminescent 4-trifluoromethy1-2-quinolones with long wave UV absorption and their use AGILENT TECHNOLOGIES, INC. 2002-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058793-A1 Luminescent 4-trifluoromethy1-2-quinolones with long wave UV absorption and their use CYP4F2, CYP4F12, CRY1 AR 4741/4885NR3C1 3087/4885PGR 4774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.