Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 12/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6678108 | 0.99 | PTGIR (0.44) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| SCHEMBL6675283 | 0.87 | ADRA2A (0.47) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| Hydrochloric Acid SCHEMBL6677488 | 0.86 | ADRA2A (0.49) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| SCHEMBL6677581 | 0.85 | AOC3 (0.45) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| SCHEMBL6676318 | 0.82 | PTGIR (0.47) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| SCHEMBL6678176 | 0.82 | PTGIR (0.47) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| SCHEMBL6676057 | 0.82 | PTGIR (0.47) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| Hydrochloric Acid SCHEMBL6675082 | 0.81 | PTGIR (0.46) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| SCHEMBL6675026 | 0.81 | PTGIR (0.49) | PTGIRADRA2AADRA2BADRA2CCACNA1C | |
| Hydrochloric Acid SCHEMBL6677779 | 0.81 | ADRA2A (0.48) | PTGIRADRA2AADRA2BADRA2CCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |