Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 20/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.48 |
| ▸ | HNF4A | P41235 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 4/20 | 0.45 |
| ▸ | RXRG | P48443 | 4/20 | 0.45 |
| ▸ | RARA | P10276 | 2/20 | 0.44 |
| ▸ | RARB | P10826 | 2/20 | 0.44 |
| ▸ | RARG | P13631 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673775 | 0.99 | RXRA (0.57) | RXRAPPARGNR1H3HNF4ARXRB | |
| SCHEMBL4956986 | 0.91 | RXRA (0.49) | RXRAPPARGNR1H3HNF4ARXRB | |
| SCHEMBL4958378 | 0.89 | RXRA (0.46) | RXRAPPARGNR1H3HNF4ARXRB | |
| SCHEMBL6686555 | 0.89 | RXRA (0.46) | RXRAPPARGNR1H3HNF4ARXRB | |
| SCHEMBL6684838 | 0.87 | RXRA (0.46) | RXRAPPARGNR1H3HNF4ARXRB | |
| SCHEMBL6675620 | 0.87 | RXRA (0.65) | RXRAPPARGNR1H3HNF4ARXRB | |
| SCHEMBL4959128 | 0.87 | RXRA (0.67) | RXRAPPARGNR1H3HNF4ARXRB | |
| SCHEMBL20178976 | 0.86 | RXRA (0.65) | RXRAHNF4ARXRBRXRGRARA | |
| SCHEMBL4959698 | 0.85 | RXRA (0.55) | RXRAPPARGNR1H3HNF4ARXRB | |
| SCHEMBL4959141 | 0.81 | RXRA (0.56) | RXRAPPARGNR1H3HNF4ARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930005-A1 | Stabilized formulation of selective ligands of retinoic acid gamma-receptors | Johnson and Johnson Consumer Companies, Inc. (US) | 2008-06-11 | — | — | EP | disclosed |
| EP-0862554-B1 | AROMATIC CARBOXYLIC ACID ESTERS, THE PRODUCTION OF SAME AND USE OF SAME AS MEDICAMENTS | HOFFMANN LA ROCHE (CH) | 2004-10-20 | — | — | EP | disclosed |
| US-5958956-A | SKIN DISORDERS; WOUND HEALING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1999-09-28 | — | — | US | disclosed |
| EP-0862554-A1 | AROMATIC CARBOXYLIC ACID ESTERS, THE PRODUCTION OF SAME AND USE OF SAME AS MEDICAMENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-09-09 | — | — | EP | disclosed |
| US-5726191-A | TREATEMENT OF LIGHT AND AGE DAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1998-03-10 | — | — | US | disclosed |
| WO-1997018192-A1 | AROMATIC CARBOXYLIC ACID ESTERS, THE PRODUCTION OF SAME AND USE OF SAME AS MEDICAMENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1997-05-22 | — | — | WO | disclosed |