Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAD52 | P43351 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679508 | 0.93 | IDO1 (0.41) | IDO1BCHEACHEPOLBRAD52 | |
| SCHEMBL5455035 | 0.90 | IDO1 (0.41) | IDO1BCHEACHEPOLBNPC1 | |
| SCHEMBL6676529 | 0.85 | IDO1 (0.39) | IDO1BCHEACHEPOLBKMT2A | |
| SCHEMBL6676039 | 0.83 | RAD52 (0.48) | IDO1POLBRAD52KMT2AHPGD | |
| SCHEMBL5450923 | 0.82 | IDO1 (0.46) | IDO1ACHEPOLBRAD52HPGD | |
| SCHEMBL6675510 | 0.82 | RAD52 (0.51) | POLBRAD52NPC1SLC2A1APOBEC3A | |
| SCHEMBL25208697 | 0.81 | ALDH1A1 (0.45) | IDO1POLBKMT2AHPGDALDH1A1 | |
| SCHEMBL6365368 | 0.80 | POLB (0.49) | POLBRAD52SLC2A1RAB9AKMT2A | |
| SCHEMBL6366253 | 0.80 | TSHR (0.53) | BCHEACHEPOLBRAD52NPC1 | |
| SCHEMBL14428363 | 0.79 | IDO1 (0.47) | IDO1BCHEACHEHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1468688-A2 | Benzoazine mono-N-oxides and benzoazine 1,4 dioxides and compositions therefrom for the therapeutic use in cancer treatments | Auckland Uniservices Limited (NZ) | 2004-10-20 | — | — | EP | disclosed |