SCHEMBL6676528

SCHEMBL6676528

NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.41
GSTK1 Q9Y2Q3 1/20 0.41
ECE1 P42892 4/20 0.37
GLO1 Q04760 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
MMP8 P22894 1/20 0.34
ITGB3 P05106 6/20 0.34
ITGB1 P05556 5/20 0.34
ITGAV P06756 5/20 0.34
ITGA5 P08648 5/20 0.34
MDM4 O15151 2/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
PTGS2 P35354 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
MDM2 Q00987 4/20 0.34
GRIA1 P42261 1/20 0.33
GRIA3 P42263 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9096940 0.97 PTGS1 (0.39) PTGS1GSTK1ECE1GLO1MEN1
SCHEMBL901070 0.97 PTGS1 (0.43) PTGS1GSTK1ECE1GLO1MEN1
SCHEMBL6928953 0.97 PTGS1 (0.43) PTGS1GSTK1ECE1GLO1MEN1
SCHEMBL6129326 0.97 PTGS1 (0.43) PTGS1GSTK1ECE1GLO1MEN1
SCHEMBL16094750 0.97 PTGS1 (0.43) PTGS1GSTK1ECE1GLO1MEN1
SCHEMBL7996840 0.96 PTGS1 (0.40) PTGS1GSTK1ECE1GLO1MEN1
SCHEMBL9180258 0.96 PTGS1 (0.40) PTGS1GSTK1ECE1GLO1MEN1
SCHEMBL5507559 0.96 PTGS1 (0.40) PTGS1GSTK1ECE1GLO1MEN1
SCHEMBL1474872 0.96 PTGS1 (0.40) PTGS1GSTK1ECE1GLO1MEN1
SCHEMBL8722673 0.94 PTGS1 (0.39) PTGS1GSTK1ECE1GLO1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004048550-A2 IMMUNE RESPONSE ASSOCIATED PROTEINS INCYTE CORPORATION (US) 2004-06-10 WO claimed
EP-1339845-A2 ADIPOCYTE COMPLEMENTED RELATED PROTEIN ZACRP3X2 ZymoGenetics, Inc. (US) 2003-09-03 EP claimed
WO-2002046417-A2 ADIPOCYTE COMPLEMENT RELATED PROTEIN ZACRP3X2 ZYMOGENETICS, INC. (US) 2002-06-13 WO claimed
CN-1158386-C Polynucleotides isolated from skin cells and methods of use thereof 吉尼西斯研究及发展有限公司 2004-07-21 CN disclosed
EP-1232174-A4 COMPOSITIONS AND METHODS FOR COUNTERACTING EFFECTS OF REACTIVE OXYGEN SPECIES AND FREE RADICALS CEREMEDIX INC (US) 2004-03-31 EP disclosed
US-6692748-B2 FAT PROTEIN; ANIMAL MODELS; HEMOSTATIC AGENTS; WOUND HEALING AGENTS ZYMOGENETICS, INC. 2004-02-17 US disclosed
CN-1376693-A Polypeptide-human liposecretion protein-27.06 and polynucleotide for coding it BIOWINDOW GENE DEV INC (CN) 2002-10-30 CN disclosed
CN-1373774-A Compositions isolated from skin cells and methods for their use GENESIS RES & DEV CORP LTD (NZ) 2002-10-09 CN disclosed
EP-1232174-A1 COMPOSITIONS AND METHODS FOR COUNTERACTING EFFECTS OF REACTIVE OXYGEN SPECIES AND FREE RADICALS Ceremedix, Inc (US) 2002-08-21 EP disclosed
CN-1307637-A Polynucleotides isolated from skin cells and methods of use thereof GENESIS RES & DEV CORP LTD (NZ) 2001-08-08 CN disclosed
WO-2001036454-A1 COMPOSITIONS AND METHODS FOR COUNTERACTING EFFECTS OF REACTIVE OXYGEN SPECIES AND FREE RADICALS CEREMEDIX, INC. (US) 2001-05-25 WO disclosed