Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 4/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | QRFPR | Q96P65 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.34 |
| ▸ | ITGAV | P06756 | 4/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.34 |
| ▸ | MDM4 | O15151 | 2/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1474872 | 1.00 | PTGS1 (0.40) | PTGS1GSTK1ECE1GLO1QRFPR | |
| SCHEMBL8434776 | 0.99 | PTGS1 (0.39) | PTGS1GSTK1ECE1GLO1QRFPR | |
| SCHEMBL8046861 | 0.99 | PTGS1 (0.39) | PTGS1GSTK1ECE1GLO1QRFPR | |
| SCHEMBL29591926 | 0.99 | PTGS1 (0.39) | PTGS1GSTK1ECE1GLO1QRFPR | |
| SCHEMBL8722673 | 0.99 | PTGS1 (0.39) | PTGS1GSTK1ECE1GLO1QRFPR | |
| SCHEMBL3706491 | 0.97 | PTGS1 (0.42) | PTGS1GSTK1ECE1GLO1MEN1 | |
| SCHEMBL547267 | 0.97 | PTGS1 (0.42) | PTGS1GSTK1ECE1GLO1MEN1 | |
| SCHEMBL9096940 | 0.96 | PTGS1 (0.39) | PTGS1GSTK1ECE1GLO1QRFPR | |
| SCHEMBL8436887 | 0.96 | PTGS1 (0.41) | PTGS1GSTK1ECE1GLO1MEN1 | |
| SCHEMBL6823837 | 0.96 | PTGS1 (0.41) | PTGS1GSTK1ECE1GLO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478796-A | Modified human immunodeficiency virus membrane protein and application thereof | 厦门大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-111918880-A | Ebola virus and marburg virus glycoprotein mucin-like domain replacement expression system as novel vaccine method | 曼尼托巴大学 | 2020-11-10 | — | — | CN | disclosed |
| CN-110049995-A | Novel human immunodeficiency's virus envelope protein antigen of mammal expression | 盖立复诊断解决方案公司 | 2019-07-23 | — | — | CN | disclosed |
| CN-100387301-C | Materials and methods for immunizing against fiv infection. | UNIV FLORIDA (US) | 2008-05-14 | — | — | CN | disclosed |
| CN-1268748-C | Viral vaccines | STRATHMANN AG & CO (DE) | 2006-08-09 | — | — | CN | disclosed |
| CN-1812810-A | Materials and methods for immunization against FIV infection | UNIV FLORIDA (US) | 2006-08-02 | — | — | CN | disclosed |
| CN-1425072-A | Gene therapy in HIV-positive patients by expression of membrane-anchored gp41 peptide | PETTE HEINRICH INST (DE) | 2003-06-18 | — | — | CN | disclosed |
| EP-0693937-A4 | HIV-1 VACCINES, ANTIBODY COMPOSITIONS RELATED THERETO, AND THERAPEUTIC AND PROPHYLACTIC USES THEREOF | PROGENICS PHARM INC (US) | 2000-03-29 | — | — | EP | disclosed |
| EP-0693937-A1 | HIV-1 VACCINES, ANTIBODY COMPOSITIONS RELATED THERETO, AND THERAPEUTIC AND PROPHYLACTIC USES THEREOF | PROGENICS PHARMACEUTICALS, INC. (US) | 1996-01-31 | — | — | EP | disclosed |
| WO-1994022477-A1 | HIV-1 VACCINES, ANTIBODY COMPOSITIONS RELATED THERETO, AND THERAPEUTIC AND PROPHYLACTIC USES THEREOF | PROGENICS PHARMACEUTICALS, INC. (US) | 1994-10-13 | — | — | WO | disclosed |