Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.53 |
| ▸ | PPARA | Q07869 | 4/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.53 |
| ▸ | DNTT | P04053 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GSTA2 | P09210 | 2/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GSTM1 | P09488 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10562109 | 0.71 | PPARG (0.43) | PPARGPPARAPPARDDNTTGBA1 | |
| SCHEMBL11757677 | 0.71 | PPARG (0.43) | PPARGPPARAPPARDDNTTGBA1 | |
| SCHEMBL11763240 | 0.71 | PPARG (0.40) | PPARGPPARAPPARDDNTTGBA1 | |
| SCHEMBL5616444 | 0.70 | PPARG (1.00) | PPARGPPARAPPARDTSHRALDH1A1 | |
| SCHEMBL5612837 | 0.70 | PPARG (1.00) | PPARGPPARAPPARDTSHRALDH1A1 | |
| SCHEMBL11764825 | 0.70 | PPARG (0.42) | PPARGPPARAPPARDDNTTGBA1 | |
| SCHEMBL10563094 | 0.70 | PPARG (0.42) | PPARGPPARAPPARDDNTTGBA1 | |
| SCHEMBL10562939 | 0.69 | PPARG (0.47) | PPARGPPARAPPARDDNTTGBA1 | |
| SCHEMBL10559876 | 0.69 | PPARG (0.47) | PPARGPPARAPPARDDNTTGBA1 | |
| SCHEMBL10561194 | 0.69 | PPARG (0.44) | PPARGPPARAPPARDDNTTGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112742-B1 | REMEDIES OR PREVENTIVES CONTAINING CYCLOPENTENONE COMPOUNDS AS THE ACTIVE INGREDIENT | TAKARA BIO INC (JP) | 2004-11-03 | — | — | EP | claimed |
| EP-1112742-B1 | REMEDIES OR PREVENTIVES CONTAINING CYCLOPENTENONE COMPOUNDS AS THE ACTIVE INGREDIENT | TAKARA BIO INC (JP) | 2004-11-03 | — | — | EP | disclosed |