SCHEMBL6676642

SCHEMBL6676642

[CH2]c1ccc(O)cc1CCCC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.61
ALOX5 P09917 5/20 0.53
CYP3A4 P08684 3/20 0.53
TP53 P04637 2/20 0.53
MEN1 O00255 1/20 0.53
MAPT P10636 1/20 0.53
ALOX15 P16050 1/20 0.53
TSHR P16473 1/20 0.53
HTT P42858 1/20 0.53
KMT2A Q03164 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
ALDH1A1 P00352 2/20 0.46
GAA P10253 1/20 0.46
ERAP1 Q9NZ08 1/20 0.46
ESR1 P03372 3/20 0.42
ESR2 Q92731 1/20 0.42
PTGS2 P35354 5/20 0.41
ADRA2A P08913 2/20 0.41
ADORA3 P0DMS8 2/20 0.41
TACR2 P21452 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6522032 0.88 TYR (0.46) TYRALOX5CYP3A4TP53MEN1
SCHEMBL9339634 0.82 TYR (0.74) TYRALOX5CYP3A4TP53MEN1
SCHEMBL8022916 0.81 HSD17B3 (0.43) TYRALOX5CYP3A4TP53MEN1
SCHEMBL7902743 0.81 TYR (0.61) TYRALOX5CYP3A4TP53MEN1
SCHEMBL26849 0.80 TYR (0.71) TYRALOX5CYP3A4TP53MEN1
SCHEMBL30223636 0.80 TYR (0.71) TYRALOX5CYP3A4TP53MEN1
SCHEMBL1237905 0.80 TYR (0.66) TYRALOX5CYP3A4TP53MEN1
SCHEMBL10921380 0.79 TYR (0.65) TYRALOX5CYP3A4TP53MEN1
SCHEMBL60292 0.78 TYR (0.63) TYRALOX5CYP3A4TP53MEN1
SCHEMBL4563615 0.78 TYR (0.69) TYRALOX5CYP3A4TP53MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109880347-A Polyurethane materials 禾聚实业有限公司 2019-06-14 CN claimed
EP-0970080-A1 IMINO-AZA-ANTHRACYCLINONE DERIVATIVES FOR THE TREATMENT OF AMYLOIDOSIS PHARMACIA & UPJOHN S.p.A. (IT) 2000-01-12 EP claimed
WO-1998032754-A1 IMINO-AZA-ANTHRACYCLINONE DERIVATIVES FOR THE TREATMENT OF AMYLOIDOSIS PHARMACIA & UPJOHN S.P.A. (IT) 1998-07-30 WO claimed
CN-109880347-A Polyurethane materials 禾聚实业有限公司 2019-06-14 CN disclosed
CN-108264858-A A kind of new A B glue being bonded for acryl plates and preparation method thereof 浙江天和树脂有限公司 2018-07-10 CN disclosed
CN-104395077-B Demoulding biaxially oriented polyester film 尤尼吉可株式会社 2017-06-09 CN disclosed
CN-106414686-A Lubricating composition 国际壳牌研究有限公司 2017-02-15 CN disclosed
CN-102282003-B For the label film of deep-draw method TREOFAN GERMANY GMBH & CO.KG (DE) 2015-08-12 CN disclosed
CN-102445719-B Protection sheet and polarizing plate JIRO CORPORATE PLAN INC 2014-09-03 CN disclosed
CN-102445717-B Protection sheet and polarizing plate JIRO CORPORATE PLAN INC 2014-09-03 CN disclosed
CN-103497713-A Adhesive composition CORIUM INT INC 2014-01-08 CN disclosed
CN-1942472-A Reverse-turn mimetics and method relating thereto CHOONGWAE PHARMA CORP (KR) 2007-04-04 CN disclosed
CN-1798746-A Reverse turn mimetics and methods relating thereto CHOONGWAE PHARMA CORP (KR) 2006-07-05 CN disclosed
WO-2004039877-A2 STABILISING AGENT MIXTURE BASF AKTIENGESELLSCHAFT (DE) 2004-05-13 WO disclosed
EP-0970080-A1 IMINO-AZA-ANTHRACYCLINONE DERIVATIVES FOR THE TREATMENT OF AMYLOIDOSIS PHARMACIA & UPJOHN S.p.A. (IT) 2000-01-12 EP disclosed
WO-1998032754-A1 IMINO-AZA-ANTHRACYCLINONE DERIVATIVES FOR THE TREATMENT OF AMYLOIDOSIS PHARMACIA & UPJOHN S.P.A. (IT) 1998-07-30 WO disclosed
EP-0672031-A1 CATECHOL DIETHERS AS SELECTIVE PDE IV? INHIBITORS PFIZER INC. (US) 1995-09-20 EP disclosed
WO-1994012461-A1 CATECHOL DIETHERS AS SELECTIVE PDEIV INHIBITORS PFIZER INC. (US) 1994-06-09 WO disclosed
EP-0252877-A1 Synergistic stabilizing mixture CIBA-GEIGY AG (CH) 1988-01-13 EP disclosed
US-4259534-A Method for the production of 2,4,6-tri(3,5-ditertiary butyl-4-hydroxybenzyl) mesitylene GURVICH YAKOV A 1981-03-31 US disclosed