Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 8/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676642 | 0.88 | TYR (0.61) | TYRESR1ESR2CYP3A4TSHR | |
| SCHEMBL8022916 | 0.85 | HSD17B3 (0.43) | TYRESR1ESR2HSD17B3CYP3A4 | |
| SCHEMBL9386903 | 0.81 | HTR2C (0.46) | TYRESR1ESR2CYP3A4TSHR | |
| SCHEMBL10825810 | 0.80 | TYR (0.55) | TYRESR1ESR2HSD17B3CYP3A4 | |
| SCHEMBL31613067 | 0.80 | TYR (0.55) | TYRESR1ESR2HSD17B3CYP3A4 | |
| SCHEMBL5931864 | 0.78 | ESR1 (0.58) | TYRESR1ESR2HSD17B3CYP3A4 | |
| SCHEMBL30014025 | 0.78 | ESR1 (0.55) | TYRESR1ESR2HSD17B3CYP3A4 | |
| SCHEMBL70464 | 0.78 | ESR1 (0.55) | TYRESR1ESR2HSD17B3CYP3A4 | |
| SCHEMBL9100129 | 0.77 | CNR1 (0.45) | ALOX5HMGCRCNR1CNR2 | |
| SCHEMBL1069010 | 0.77 | TAAR1 (0.41) | TSHRMEN1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050112693-A1 | Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof | NEFZI ADEL (US) | 2005-05-26 | — | — | US | claimed |
| US-20030120066-A1 | Synthetic peptides | NEFZI ADEL (US) | 2003-06-26 | — | — | US | claimed |
| US-6809202-B2 | SYNTHETIC PEPTIDES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES | 2004-10-26 | — | — | US | disclosed |
| US-20030120066-A1 | Synthetic peptides | NEFZI ADEL (US) | 2003-06-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050112693-A1 | Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof | DHPS, DCK, DAZAP1 | TYR 4244/4885ESR1 4384/4885ESR2 4180/4885 |
| US-20030120066-A1 | Synthetic peptides | VIP, NGLY1, GRPR | TYR 4160/4885ESR1 4195/4885ESR2 3313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.