SCHEMBL6676785

SCHEMBL6676785

CO[CH]CCCOC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2088240 0.81
SCHEMBL3322648 0.81
SCHEMBL28225716 0.78
SCHEMBL6468714 0.78
SCHEMBL8535707 0.78
SCHEMBL8440343 0.75 ALDH1A1 (0.35)
SCHEMBL7177863 0.74
SCHEMBL3320964 0.73
SCHEMBL1938236 0.73
SCHEMBL64399 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200071326-A1 TAM KINASE INHIBITORS SYROS PHARMACEUTICALS INC (US) 2020-03-05 US claimed
WO-2018191587-A1 TAM KINASE INHIBITORS SYROS PHARMACEUTICALS, INC. (US) 2018-10-18 WO claimed
US-20200071326-A1 TAM KINASE INHIBITORS SYROS PHARMACEUTICALS INC (US) 2020-03-05 US disclosed
WO-2018191587-A1 TAM KINASE INHIBITORS SYROS PHARMACEUTICALS, INC. (US) 2018-10-18 WO disclosed
WO-2004041799-A1 5- (SUBSTITUTED PHENYL) -THIADIAZOLIDINE-3-ONES AND THEIR USE AS PTP1B ASTRAZENECA AB (SE) 2004-05-21 WO disclosed
US-5719155-A CARDIOVASCULAR DISORDERS JAPAN TOBACCO INC. (JP) 1998-02-17 US disclosed
EP-0677519-A1 CHROMAN DERIVATIVE AND MEDICINAL USE THEREOF Japan Tobacco Inc. (JP) 1995-10-18 EP disclosed
US-4078066-A HYPOTENSIVE AGENTS, SURFACTANTS, BACTERICIDES AND WATER SOFTENERS E. R. SQUIBB & SONS, INC. (US) 1978-03-07 US disclosed
US-4033971-A HYPOTENSIVES, SURFACTANTS, BACTERICIDES, WATER SOFTENERS E. R. SQUIBB & SONS, INC. (US) 1977-07-05 US disclosed
US-4022788-A HYPERTENSIVE AGENT, SOFTENERS E. R. SQUIBB & SONS, INC. (US) 1977-05-10 US disclosed