Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864504 | 0.88 | MME (0.33) | ITGB3ITGA2B | |
| SCHEMBL1782571 | 0.86 | MME (0.33) | MAPTEPHX1ALDH1A1ITGB3ITGA2B | |
| Water SCHEMBL6244439 | 0.85 | MME (0.32) | MAPTEPHX1ALDH1A1ITGB3ITGA2B | |
| SCHEMBL22529222 | 0.82 | CYP4F2 (0.31) | GAAMEN1KMT2AITGB3ITGA2B | |
| SCHEMBL3525418 | 0.74 | CA12 (0.42) | MAPTEPHX1ALDH1A1EPHX2 | |
| SCHEMBL515555 | 0.72 | ALDH1A1 (0.47) | MAPTEPHX1KDM4EPOLBALDH1A1 | |
| SCHEMBL7277999 | 0.71 | EPHX1 (0.46) | EPHX1BTKGAAKDM4EPOLB | |
| SCHEMBL159315 | 0.70 | ALDH1A1 (0.50) | MAPTEPHX1KDM4EPOLBALDH1A1 | |
| Hydrochloric Acid SCHEMBL8591556 | 0.70 | ALDH1A1 (0.45) | KDM4ELMNAPOLBALDH1A1MEN1 | |
| SCHEMBL250459 | 0.70 | ALDH1A1 (0.50) | MAPTEPHX1KDM4EPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0813544-B1 | BRADYKININ ANTAGONIST PEPTIDES INCORPORATING N-SUBSTITUTED GLYCINES | CORTECH INC (US) | 2004-10-27 | — | — | EP | disclosed |