Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | SNCA | P37840 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | PYGM | P11217 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.54 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676810 | 1.00 | MEN1 (0.61) | MEN1KMT2ASNCAPOLBRAB9A | |
| SCHEMBL7643672 | 0.92 | MEN1 (0.60) | MEN1KMT2ASNCAPOLBRAB9A | |
| SCHEMBL7643669 | 0.92 | MEN1 (0.60) | MEN1KMT2ASNCAPOLBRAB9A | |
| SCHEMBL6677951 | 0.91 | KDM4E (0.58) | MEN1KMT2ASNCARAB9ANPC1 | |
| SCHEMBL6677957 | 0.91 | KDM4E (0.58) | MEN1KMT2ASNCARAB9ANPC1 | |
| SCHEMBL6673496 | 0.85 | MEN1 (0.62) | MEN1KMT2ASNCAGFERMAPT | |
| SCHEMBL6674346 | 0.85 | MEN1 (0.62) | MEN1KMT2ASNCAGFERMAPT | |
| SCHEMBL2271821 | 0.85 | SNCA (0.61) | MEN1KMT2ASNCAPOLBRAB9A | |
| SCHEMBL2271828 | 0.85 | SNCA (0.61) | MEN1KMT2ASNCAPOLBRAB9A | |
| SCHEMBL6677116 | 0.84 | CHEK1 (0.70) | MEN1KMT2APOLBRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289936-B1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK INC (US) | 2004-10-20 | — | — | EP | claimed |
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | claimed |
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | TELIK, INC. | 2002-03-14 | — | — | US | claimed |
| EP-1289936-B1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK INC (US) | 2004-10-20 | — | — | EP | disclosed |
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | TELIK, INC. | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | SLC2A1, SLC2A8, SLC2A2 | MEN1 2354/4885KMT2A 3788/4885SNCA 3814/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.