Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.61 |
| ▸ | GFER | P55789 | 1/20 | 0.57 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.56 |
| ▸ | HNF4A | P41235 | 1/20 | 0.56 |
| ▸ | SNCA | P37840 | 3/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674346 | 1.00 | MEN1 (0.62) | MEN1KMT2APKMMAPTGRIK1 | |
| SCHEMBL6674592 | 0.90 | PTPN1 (0.56) | MEN1KMT2APKMMAPTGRIK1 | |
| SCHEMBL6675963 | 0.90 | PTPN1 (0.56) | MEN1KMT2APKMMAPTGRIK1 | |
| SCHEMBL2276655 | 0.88 | PKM (0.62) | MEN1KMT2APKMMAPTGRIK1 | |
| SCHEMBL2276651 | 0.88 | PKM (0.62) | MEN1KMT2APKMMAPTGRIK1 | |
| SCHEMBL6678169 | 0.86 | KDM4E (0.60) | MEN1KMT2AMAPTPTPN1SNCA | |
| SCHEMBL6676947 | 0.86 | KDM4E (0.60) | MEN1KMT2AMAPTPTPN1SNCA | |
| SCHEMBL6676808 | 0.85 | MEN1 (0.61) | MEN1KMT2AMAPTGFERSNCA | |
| SCHEMBL6676810 | 0.85 | MEN1 (0.61) | MEN1KMT2AMAPTGFERSNCA | |
| SCHEMBL6677951 | 0.85 | KDM4E (0.58) | MEN1KMT2AMAPTSNCAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289936-B1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK INC (US) | 2004-10-20 | — | — | EP | claimed |
| EP-1289936-B1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK INC (US) | 2004-10-20 | — | — | EP | disclosed |