Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 13/20 | 0.57 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.37 |
| ▸ | S100A9 | P06702 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SGK1 | O00141 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676981 | 1.00 | UTS2R (0.57) | UTS2RHTR2CHTR2BERBB2EPHA2 | |
| SCHEMBL6674005 | 0.92 | UTS2R (0.58) | UTS2RHTR2CHTR2BERBB2EPHA2 | |
| SCHEMBL6674000 | 0.92 | UTS2R (0.58) | UTS2RHTR2CHTR2BERBB2EPHA2 | |
| SCHEMBL6679727 | 0.91 | UTS2R (0.58) | UTS2RHTR2CHTR2BERBB2EPHA2 | |
| SCHEMBL6679730 | 0.91 | UTS2R (0.58) | UTS2RHTR2CHTR2BERBB2EPHA2 | |
| SCHEMBL6818819 | 0.90 | UTS2R (0.59) | UTS2RKDR | |
| SCHEMBL6678344 | 0.90 | UTS2R (0.62) | UTS2RHTR2CHTR2BERBB2EPHA2 | |
| SCHEMBL6678338 | 0.90 | UTS2R (0.62) | UTS2RHTR2CHTR2BERBB2EPHA2 | |
| SCHEMBL6675717 | 0.88 | UTS2R (0.64) | UTS2RERBB2EPHA2KDREPHB4 | |
| SCHEMBL6675708 | 0.88 | UTS2R (0.64) | UTS2RERBB2EPHA2KDREPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043463-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043463-A2 | SULFONAMIDES | SMITHKLINE BEECHAM CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |