Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680679 | 0.89 | ADRB3 (0.36) | HTTADRB3ADRB1ADRB2CA2 | |
| SCHEMBL6677699 | 0.88 | ADRB3 (0.37) | LMNAADRB3ADRB1ADRB2CA2 | |
| SCHEMBL6677357 | 0.87 | ADRB3 (0.37) | LMNAADRB3ADRB1ADRB2CA2 | |
| SCHEMBL6681115 | 0.87 | ADRB3 (0.37) | MAPTLMNAKMT2AMEN1ADRB3 | |
| SCHEMBL6677162 | 0.85 | ADRB3 (0.35) | MAPTLMNANPSR1KMT2AMEN1 | |
| SCHEMBL6676709 | 0.85 | MEN1 (0.32) | MAPTLMNANPSR1HTTKMT2A | |
| SCHEMBL6680598 | 0.82 | ADRB3 (0.40) | ADRB3ADRB1ADRB2CA2 | |
| SCHEMBL6679366 | 0.82 | ADRB3 (0.39) | ADRB3ADRB1ADRB2CA2 | |
| SCHEMBL6680863 | 0.82 | ADRB3 (0.47) | MAPTLMNAKMT2AMEN1ADRB3 | |
| SCHEMBL6676373 | 0.81 | ADRB3 (0.40) | ADRB3ADRB1ADRB2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |