Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 6/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677357 | 0.94 | ADRB3 (0.37) | ADRB3ADRB1ADRB2LMNAADORA1 | |
| SCHEMBL6681115 | 0.94 | ADRB3 (0.37) | ADRB3ADRB1ADRB2MAPTALDH1A1 | |
| SCHEMBL6677699 | 0.94 | ADRB3 (0.37) | ADRB3ADRB1ADRB2LMNAADORA1 | |
| SCHEMBL6680730 | 0.92 | ADRB3 (0.38) | ADRB3ADRB1ADRB2CA2 | |
| SCHEMBL6680679 | 0.87 | ADRB3 (0.36) | ADRB3ADRB1ADRB2ADORA1CA2 | |
| SCHEMBL6680598 | 0.86 | ADRB3 (0.40) | ADRB3ADRB1ADRB2CA2 | |
| SCHEMBL6678047 | 0.86 | ADRB3 (0.39) | ADRB3ADRB1ADRB2CA2 | |
| SCHEMBL6677086 | 0.85 | MAPT (0.36) | ADRB3ADRB1ADRB2MAPTALDH1A1 | |
| SCHEMBL6679264 | 0.85 | ADRB3 (0.36) | ADRB3ADRB1ADRB2MAPTALDH1A1 | |
| SCHEMBL6803783 | 0.83 | BACE1 (0.36) | ADRB3ADRB1ADRB2PTGER4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |