Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 6/20 | 0.52 |
| ▸ | FPR2 | P25090 | 1/20 | 0.49 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677141 | 1.00 | ACACB (0.52) | ACACBFPR2LDHAESR1KCNH2 | |
| SCHEMBL1412207 | 0.92 | ACACB (0.59) | ACACBFPR2LDHAESR1KCNH2 | |
| SCHEMBL6676699 | 0.89 | MTNR1A (0.48) | ACACBESR1KCNH2 | |
| SCHEMBL6541155 | 0.89 | MTNR1A (0.48) | ACACBESR1KCNH2 | |
| SCHEMBL6679787 | 0.86 | ESR1 (0.47) | ACACBESR1KCNH2 | |
| SCHEMBL6541556 | 0.86 | ESR1 (0.47) | ACACBESR1KCNH2 | |
| SCHEMBL6805895 | 0.86 | ESR1 (0.47) | ACACBESR1KCNH2 | |
| SCHEMBL6806643 | 0.84 | ACACB (0.41) | ACACBFPR2 | |
| SCHEMBL6541208 | 0.84 | CNR1 (0.56) | ACACBFPR2LDHA | |
| SCHEMBL6804725 | 0.82 | ESR1 (0.43) | ACACBESR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | ACACB 1800/4885FPR2 998/4885LDHA 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.