SCHEMBL667723

SCHEMBL667723

COc1cccc(C(=O)NN)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.68
RAB9A P51151 6/20 0.68
MEN1 O00255 1/20 0.66
KMT2A Q03164 1/20 0.66
PARP1 P09874 1/20 0.66
CES2 O00748 1/20 0.65
CES1 P23141 1/20 0.65
SMN1; SMN2 Q16637 4/20 0.64
KDM4E B2RXH2 2/20 0.64
ALDH1A1 P00352 2/20 0.64
LMNA P02545 1/20 0.64
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
TSHR P16473 2/20 0.62
NPSR1 Q6W5P4 1/20 0.62
TAS1R3 Q7RTX0 1/20 0.61
TAS1R1 Q7RTX1 1/20 0.61
RXFP1 Q9HBX9 1/20 0.61
TP53 P04637 2/20 0.60
KCNK3 O14649 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29598340 1.00 NPC1 (0.68) NPC1RAB9AMEN1KMT2APARP1
SCHEMBL5552356 0.94 NPC1 (0.60) NPC1RAB9AMEN1KMT2APARP1
SCHEMBL7229522 0.89 NPC1 (0.64) NPC1RAB9AMEN1KMT2APARP1
SCHEMBL18311276 0.86 NPC1 (0.73) NPC1RAB9AMEN1KMT2APARP1
SCHEMBL4331173 0.86 RAB9A (0.68) NPC1RAB9AMEN1KMT2APARP1
SCHEMBL30184362 0.86 RAB9A (0.68) NPC1RAB9AMEN1KMT2APARP1
SCHEMBL12871351 0.85 NPC1 (0.90) NPC1RAB9AMEN1KMT2APARP1
Water SCHEMBL8856896 0.85 NPC1 (0.53) NPC1RAB9AMEN1KMT2APARP1
SCHEMBL16461033 0.84 RAB9A (0.70) NPC1RAB9AMEN1KMT2APARP1
SCHEMBL30416225 0.84 NPC1 (0.70) NPC1RAB9AMEN1KMT2APARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 283 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115308405-A Kit for quantitatively detecting anti-myeloperoxidase antibody IgG 海茵生物科技(北京)有限公司 2022-11-08 CN claimed
CN-110003160-B Osthole hydrazone/acylhydrazone/sulfonylhydrazone derivatives, and preparation method and application thereof 贵州中医药大学 2022-10-11 CN claimed
CN-110003160-A A kind of Osthole hydrazone class/acylhydrazone class/sulphur acylhydrazone and preparation method thereof and application 贵州中医药大学 2019-07-12 CN claimed
CN-106397420-B 3- (5- aryl-1,3,4-oxdiazole -2- bases) asarinin analog derivative, preparation method and application 郑州大学 2018-10-09 CN claimed
CN-108623625-A With active organic vanadium complex of para-insulin and preparation method thereof 山东理工大学 2018-10-09 CN claimed
CN-106380475-B A kind of thieno [2,3 d] pyrimidines and its preparation method and application 湖北民族学院 2018-03-09 CN claimed
CN-106397420-A 3-(5-aryl-1,3-4-oxadiazole-2-yl)sarisan derivatives, and preparation method and application thereof 郑州大学 2017-02-15 CN claimed
CN-106380475-A Thieno [2, 3-d] pyrimidine compound, preparation method thereof and application thereof 湖北民族学院 2017-02-08 CN claimed
CN-104177459-A 1,3,4-oxadiazole derivative containing glucosamine fragment as well as synthetic method and use of derivative HUAIHAI INST TECHNOLOGY 2014-12-03 CN claimed
CN-104151371-A N-acetylglucosamine-N'-acylamino thiourea as well as synthesis method and application thereof HUAIHAI INST TECHNOLOGY 2014-11-19 CN claimed
CN-103130766-B Piperine hydrazone or acylhydrazone or sulfonyl hydrazone derivative substances and application for preparing a botanical insecticide UNIV NORTHWEST A&F 2014-06-11 CN claimed
CN-103130766-A Piperine hydrazone or acylhydrazone or sulfonyl hydrazone derivative substances and application for preparing a botanical insecticide UNIV NORTHWEST A&F 2013-06-05 CN claimed
CN-101914611-B Kit and method for clinical detection of myeloperoxidase NINGBO MEDICAL SYSTEM BIOTECHNOLOGY CO LTD 2012-10-03 CN claimed
CN-101914611-A Kit and method for clinical detection of myeloperoxidase NINGBO MEDICAL SYSTEM BIOTECHNOLOGY CO LTD 2010-12-15 CN claimed
EP-4610260-A1 ARYL HETEROCYCLIC KV1.3 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF Shanghai Shenshi Wise Technology Co., Ltd. (CN) 2025-09-03 EP disclosed
CN-119790057-A Novel PLK1 degradation inducing compounds 厄普特拉株式会社 2025-04-08 CN disclosed
CN-119504731-A Naringenin derivative containing 1,3, 4-oxadiazole acylhydrazone structure and preparation method thereof 广东省科学院测试分析研究所(中国广州分析测试中心) 2025-02-25 CN disclosed
US-5173492-A Bronchodilator agents KYOWA HAKKO KOGYO CO., LTD. (JP) 1992-12-22 US disclosed
US-5120347-A Pre and postemergence ROHM AND HAAS COMPANY (US) 1992-06-09 US disclosed
EP-0417790-A2 S-triazolo[3,4-i]purine derivatives KYOWA HAKKO KOGYO CO., LTD. (JP) 1991-03-20 EP disclosed