Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.60 |
| ▸ | CNR1 | P21554 | 1/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | APAF1 | O14727 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.57 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.57 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1902817 | 0.85 | TDP1 (0.64) | TDP1HPGDMAPTABCC4CNR1 | |
| SCHEMBL3294983 | 0.85 | TDP1 (0.64) | TDP1HPGDMAPTABCC4CNR1 | |
| SCHEMBL9481543 | 0.82 | TDP1 (0.81) | TDP1HPGDMAPTABCC4CNR1 | |
| SCHEMBL9480984 | 0.81 | TDP1 (0.85) | TDP1HPGDMAPTABCC4CNR1 | |
| SCHEMBL11133665 | 0.81 | TDP1 (0.85) | TDP1HPGDMAPTABCC4CNR1 | |
| SCHEMBL17430786 | 0.80 | TDP1 (0.77) | TDP1HPGDMAPTABCC4CNR1 | |
| SCHEMBL5564580 | 0.80 | TDP1 (0.77) | TDP1HPGDMAPTABCC4CNR1 | |
| SCHEMBL13287328 | 0.79 | TDP1 (0.76) | TDP1HPGDMAPTABCC4CNR1 | |
| SCHEMBL10818952 | 0.79 | TDP1 (0.73) | TDP1HPGDMAPTABCC4CNR1 | |
| SCHEMBL10818943 | 0.79 | TDP1 (0.73) | TDP1HPGDMAPTABCC4CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037832-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF CEFIXIME | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2004-05-06 | — | — | WO | disclosed |
| US-20040082560-A1 | Process for the preparation of cefixime | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082560-A1 | Process for the preparation of cefixime | CYP4F8, CYP4X1, CYP3A5 | TDP1 4635/4885HPGD 436/4885MAPT 4048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.