⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8572245 | 0.79 | — | — | |
| SCHEMBL10433023 | 0.72 | — | — | |
| SCHEMBL14946895 | 0.71 | ALDH1A1 (0.56) | — | |
| SCHEMBL10401885 | 0.71 | ALDH1A1 (0.56) | — | |
| SCHEMBL21430284 | 0.69 | — | — | |
| SCHEMBL2626776 | 0.69 | — | — | |
| SCHEMBL17087048 | 0.67 | — | — | |
| SCHEMBL20068650 | 0.67 | — | — | |
| SCHEMBL11907767 | 0.67 | — | — | |
| SCHEMBL10086054 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022282-B1 | Homo- and hetero metal alkylidene complexes of ruthenium with N-heterocyclic carbene ligands, and their use as highly active and selective catalysts for olefin metathesis | DEGUSSA (DE) | 2004-10-20 | — | — | EP | disclosed |
| US-6787620-B2 | USEFUL AS CATALYST FOR OLEFIN METATHESIS | DEGUSSA AG (DE) | 2004-09-07 | — | — | US | disclosed |
| US-20030149274-A1 | Homobimetallic and heterobimetallic alkylidene complexes of ruthenium containing N-heterocyclic carbene ligands | EVONIK DEGUSSA GMBH (DE) | 2003-08-07 | — | — | US | disclosed |
| US-6552139-B1 | Process for preparing acyclic olefins using homobimetallic and heterobimetallic alkylidene complexes of ruthenium containing N-heterocyclic carbene ligands | DEGUSSA AG (DE) | 2003-04-22 | — | — | US | disclosed |
| EP-1022282-A2 | Homo- and hetero metal alkylidene complexes of ruthenium with N-heterocyclic carbene ligands, and their use as highly active and selective catalysts for olefin metathesis | Aventis Research & Technologies GmbH & Co. KG (DE) | 2000-07-26 | — | — | EP | disclosed |