Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.45 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.39 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.39 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.39 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 8/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805535 | 0.89 | CNR1 (0.43) | CNR1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6805794 | 0.86 | MAPT (0.42) | CNR1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6809238 | 0.82 | CNR1 (0.46) | CNR1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6681814 | 0.82 | CNR1 (0.48) | CNR1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6540840 | 0.81 | NAMPT (0.45) | CNR1ACACBKMT2A | |
| SCHEMBL6680778 | 0.79 | CNR1 (0.40) | CNR1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL6541239 | 0.79 | CNR1 (0.44) | CNR1ACACBALDH1A1ESR1KCNH2 | |
| SCHEMBL6806001 | 0.78 | ACACB (0.45) | CNR1ACACBALDH1A1KMT2ACYP3A4 | |
| SCHEMBL6540590 | 0.78 | ACACB (0.45) | CNR1ACACBALDH1A1KMT2ACYP3A4 | |
| SCHEMBL6541208 | 0.78 | CNR1 (0.56) | CNR1ACACBALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | CNR1 112/4885ABCC9 1596/4885ABCC8 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.