Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.45 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | ACACB | O00763 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552876 | 0.90 | ESR1 (0.39) | NAMPTCNR1ACACBKMT2A | |
| SCHEMBL6541239 | 0.89 | CNR1 (0.44) | NAMPTCNR1ACACB | |
| SCHEMBL6541730 | 0.89 | CNR1 (0.38) | NAMPTCNR1ACACBMEN1KMT2A | |
| SCHEMBL6806001 | 0.88 | ACACB (0.45) | NAMPTCNR1ACACBKMT2A | |
| SCHEMBL6540590 | 0.88 | ACACB (0.45) | NAMPTCNR1ACACBKMT2A | |
| SCHEMBL6541794 | 0.88 | PTPN1 (0.44) | NAMPTCNR1ACACB | |
| SCHEMBL6552874 | 0.88 | ESR1 (0.38) | NAMPTCNR1ACACB | |
| SCHEMBL6540415 | 0.86 | CNR1 (0.40) | CNR1ACACB | |
| SCHEMBL6541208 | 0.84 | CNR1 (0.56) | CNR1ACACB | |
| SCHEMBL6540898 | 0.83 | ABCC9 (0.57) | NAMPTMEP1BCNR1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138462-A1 | Aminoalcohol derivatives | BPHL, FANCD2, HRH2 | NAMPT 4409/4885MEP1B 3466/4885CNR1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.