Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.70 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.65 |
| ▸ | MEN1 | O00255 | 9/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 8/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680626 | 0.89 | ALDH1A1 (0.83) | ALDH1A1KDM4EKDM5BKMT2AMEN1 | |
| SCHEMBL6689859 | 0.86 | KDM5B (0.67) | ALDH1A1KDM4EKDM5BKMT2AMEN1 | |
| SCHEMBL6670517 | 0.85 | ALDH1A1 (0.69) | ALDH1A1KDM4EKDM5BKMT2AMEN1 | |
| SCHEMBL6683085 | 0.82 | ALDH1A1 (0.72) | ALDH1A1KDM4EKDM5BKMT2AMEN1 | |
| SCHEMBL6682286 | 0.82 | ALDH1A1 (0.72) | ALDH1A1KDM4EKDM5BKMT2AMEN1 | |
| SCHEMBL6678026 | 0.82 | ALDH1A1 (0.72) | ALDH1A1KDM4EKDM5BKMT2AMEN1 | |
| SCHEMBL6677471 | 0.82 | ALDH1A1 (0.72) | ALDH1A1KDM4EKDM5BKMT2AMEN1 | |
| SCHEMBL6677490 | 0.82 | KMT2A (0.89) | ALDH1A1KDM4EKDM5BKMT2AMEN1 | |
| SCHEMBL6677044 | 0.81 | ALDH1A1 (0.70) | ALDH1A1KDM4EKDM5BKMT2AMEN1 | |
| SCHEMBL6670526 | 0.80 | ALDH1A1 (0.70) | ALDH1A1KDM4EKDM5BKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |