Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | APP | P05067 | 4/20 | 0.51 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6754285 | 0.84 | MAOA (0.64) | CYP1A2APPHRH1MAOAMAOB | |
| SCHEMBL27513658 | 0.82 | CYP1A2 (1.00) | CYP1A2APPHRH1MKNK1HRH3 | |
| SCHEMBL1108633 | 0.82 | CYP1A2 (0.69) | CYP1A2APPMKNK1HRH3ALDH1A1 | |
| SCHEMBL4842263 | 0.80 | MAOA (0.71) | CYP1A2APPHRH1HRH3MAOA | |
| SCHEMBL4967404 | 0.80 | HRH4 (0.52) | CYP1A2APPHRH3MAOAMAOB | |
| SCHEMBL13763363 | 0.79 | CYP1A2 (0.65) | CYP1A2APPMKNK1HRH3ALDH1A1 | |
| SCHEMBL6792327 | 0.79 | HRH1 (0.62) | CYP1A2HRH1HRH3MAOAMAOB | |
| SCHEMBL13757443 | 0.78 | CYP1A2 (0.63) | CYP1A2APPMKNK1HRH3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4843995 | 0.78 | MAOA (0.69) | CYP1A2APPHRH1HRH3MAOA | |
| SCHEMBL30639140 | 0.78 | HRH4 (0.45) | HRH3ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |