Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 13/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 13/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 13/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 13/20 | 0.61 |
| ▸ | PNP | P00491 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 2/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.39 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675460 | 0.91 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL6675826 | 0.91 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL6155745 | 0.89 | PDE4A (0.79) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL6675792 | 0.86 | PNP (0.50) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL6674156 | 0.82 | PNP (0.53) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL7491119 | 0.82 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DPNP | |
| Hydrochloric Acid SCHEMBL7864182 | 0.80 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL6674800 | 0.80 | PNP (0.54) | PDE4APDE4BPDE4CPDE4DPNP | |
| SCHEMBL6673827 | 0.79 | PDE5A (0.46) | PDE4APDE4BPDE4CPDE4DPNP | |
| Hydrochloric Acid SCHEMBL7853858 | 0.78 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1202628-B1 | NOVEL HYPOXANTHINE AND THIOHYPOXANTHINE COMPOUNDS | EURO CELTIQUE SA (LU) | 2004-10-13 | — | — | EP | disclosed |