SCHEMBL6677852

SCHEMBL6677852

CCCCCC(C1=CC=CC1)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.36
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
CYSLTR2 Q9NS75 3/20 0.32
CYSLTR1 Q9Y271 3/20 0.32
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31
DRD3 P35462 1/20 0.31
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6673438 0.96 PNMT (0.37) PNMTNPC1RAB9ACYSLTR2CYSLTR1
SCHEMBL6672359 0.91 PNMT (0.38) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6674618 0.87 PNMT (0.43) PNMTNPC1RAB9ACYSLTR2CYSLTR1
SCHEMBL6671930 0.86 PNMT (0.40) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL6676496 0.83 PNMT (0.44) PNMTNPC1RAB9ACYSLTR2CYSLTR1
SCHEMBL7754318 0.81 PNMT (0.42) PNMTNPC1RAB9ACYSLTR2CYSLTR1
SCHEMBL27675984 0.80 PNMT (0.41) PNMTNPC1RAB9ACYSLTR2CYSLTR1
SCHEMBL6675789 0.78 PNMT (0.46) PNMTNPC1RAB9ADRD2DRD4
SCHEMBL1610355 0.77 PNMT (0.41) PNMTNPC1RAB9ACYSLTR2CYSLTR1
SCHEMBL27594318 0.77 PNMT (0.41) PNMTNPC1RAB9ACYSLTR2CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0963990-B1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
US-6197990-B1 REACTING CYCLOPENTADIENE AND METAL HYDRIDE IN PRESENCE OF AMINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-06 US disclosed
EP-0963990-A1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-15 EP disclosed