Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | HPGD | P15428 | 5/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.68 |
| ▸ | FBP1 | P09467 | 3/20 | 0.68 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.68 |
| ▸ | DRD2 | P14416 | 1/20 | 0.68 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.68 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.68 |
| ▸ | DRD1 | P21728 | 1/20 | 0.68 |
| ▸ | MC5R | P33032 | 1/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.68 |
| ▸ | DRD3 | P35462 | 1/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.68 |
| ▸ | CCR2 | P41597 | 1/20 | 0.68 |
| ▸ | HTR6 | P50406 | 1/20 | 0.68 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.68 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630208 | 0.85 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD17B10FBP1ALOX15 | |
| SCHEMBL18091181 | 0.85 | ALDH1A1 (0.63) | ALDH1A1HPGDHSD17B10FBP1ALOX15 | |
| SCHEMBL10474784 | 0.85 | ALDH1A1 (0.63) | ALDH1A1HPGDHSD17B10FBP1ALOX15 | |
| SCHEMBL547671 | 0.85 | ALDH1A1 (0.63) | ALDH1A1HPGDHSD17B10FBP1ALOX15 | |
| SCHEMBL11424869 | 0.82 | HPGD (0.59) | ALDH1A1HPGDHSD17B10FBP1ALOX15 | |
| SCHEMBL5675266 | 0.82 | ALDH1A1 (0.59) | ALDH1A1HPGDHSD17B10FBP1ALOX15 | |
| Benzothiazyl Disulfide SCHEMBL11095350 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HPGDHSD17B10FBP1ALOX15 | |
| SCHEMBL30005981 | 0.81 | ALDH1A1 (0.76) | ALDH1A1HPGDHSD17B10FBP1ALOX15 | |
| Benzothiazyl Disulfide SCHEMBL29356396 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HPGDHSD17B10FBP1ALOX15 | |
| SCHEMBL381557 | 0.81 | ALDH1A1 (0.76) | ALDH1A1HPGDHSD17B10FBP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6218561-B1 | REACTING A MERCAPTOALKOXYSILANE WITH A N-ALKYLBIS(BENZOTHIAZOLSULFEN)AMIDE. | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-04-17 | — | — | US | claimed |
| EP-1155076-B1 | IN SITU PREPARATION OF A BIS-(BENZOTHIAZOLESULFEN)AMIDE IN A POLYMERIC MATRIX | UNIROYAL CHEM CO INC (US) | 2004-10-20 | — | — | EP | disclosed |
| US-6573339-B1 | Reacting a mixture consisting of an N-hydrocarbyl-2-benzothiazolesulfenamide and an anhydride of an aliphatic dicarboxylic acid containing four to six carbon atoms in situ in a natural or synthetic elastomer matrix | UNIROYAL CHEMICAL COMPANY, INC. | 2003-06-03 | — | — | US | disclosed |
| US-6573339-B1 | Reacting a mixture consisting of an N-hydrocarbyl-2-benzothiazolesulfenamide and an anhydride of an aliphatic dicarboxylic acid containing four to six carbon atoms in situ in a natural or synthetic elastomer matrix | UNIROYAL CHEMICAL COMPANY, INC. | 2003-06-03 | — | — | US | disclosed |
| EP-1155076-A1 | IN SITU PREPARATION OF A BIS-(BENZOTHIAZOLESULFEN)AMIDE IN A POLYMERIC MATRIX | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 2001-11-21 | — | — | EP | disclosed |
| US-6218561-B1 | REACTING A MERCAPTOALKOXYSILANE WITH A N-ALKYLBIS(BENZOTHIAZOLSULFEN)AMIDE. | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-04-17 | — | — | US | disclosed |
| US-6218561-B1 | REACTING A MERCAPTOALKOXYSILANE WITH A N-ALKYLBIS(BENZOTHIAZOLSULFEN)AMIDE. | THE GOODYEAR TIRE & RUBBER COMPANY | 2001-04-17 | — | — | US | disclosed |
| WO-2000042099-A1 | IN SITU PREPARATION OF A BIS-(BENZOTHIAZOLESULFEN)AMIDE IN A POLYMERIC MATRIX | UNIROYAL CHEMICAL COMPANY, INC. (US) | 2000-07-20 | — | — | WO | disclosed |
| WO-1992005218-A1 | METHOD OF MANUFACTURING A NITROSAMINE-FREE RUBBER ARTICLE | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1992-04-02 | — | — | WO | disclosed |