Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9905548 | 0.92 | PTGS1 (0.37) | TSHRLMNAALDH1A1POLBKMT2A | |
| SCHEMBL665724 | 0.82 | — | — | |
| SCHEMBL6682002 | 0.80 | — | — | |
| SCHEMBL3876682 | 0.79 | PTGS1 (0.36) | TSHRLMNAPOLBKMT2ATHRB | |
| SCHEMBL3878294 | 0.79 | PTGS1 (0.36) | TSHRLMNAPOLBKMT2ATHRB | |
| SCHEMBL16341438 | 0.77 | TSHR (0.34) | TSHRALDH1A1 | |
| SCHEMBL14657732 | 0.69 | — | — | |
| SCHEMBL3883405 | 0.61 | — | — | |
| SCHEMBL19442275 | 0.61 | TSHR (0.32) | TSHRLMNAALDH1A1POLBKMT2A | |
| Hexane SCHEMBL8705498 | 0.54 | TSHR (0.88) | TSHRLMNAALDH1A1KMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1093475-B1 | CATALYST FOR THE POLYMERISATION OF OLEFINS | BOREALIS TECH OY (FI) | 2004-11-17 | — | — | EP | disclosed |
| US-6613851-B1 | Cyclic carbene- eta -ligand complexes for catalysis of olefin polymerization. | BOREALIS TECHNOLOGY OY (FI) | 2003-09-02 | — | — | US | disclosed |