Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1D | Q01668 | 6/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679547 | 0.80 | HDAC4 (0.33) | MDM2HDAC4 | |
| SCHEMBL6677869 | 0.80 | CACNA1D (0.31) | CACNA1DMDM2 | |
| SCHEMBL5614156 | 0.80 | CACNA1D (0.33) | CACNA1DHTR2AHTR2CHTR2B | |
| SCHEMBL6678329 | 0.78 | HDAC4 (0.31) | HDAC4 | |
| SCHEMBL6678116 | 0.77 | — | — | |
| SCHEMBL6681681 | 0.77 | HDAC4 (0.32) | HDAC4 | |
| SCHEMBL6677067 | 0.76 | CACNA1D (0.38) | CACNA1D | |
| SCHEMBL6677390 | 0.72 | MEN1 (0.31) | CACNA1DHTR2AHTR2CHTR2B | |
| SCHEMBL4519520 | 0.71 | CACNA1D (0.31) | CACNA1D | |
| SCHEMBL1170017 | 0.71 | CACNA1D (0.31) | CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |