Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1D | Q01668 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678329 | 0.81 | HDAC4 (0.31) | — | |
| SCHEMBL6679547 | 0.81 | HDAC4 (0.33) | MDM2 | |
| SCHEMBL6681681 | 0.80 | HDAC4 (0.32) | — | |
| SCHEMBL6678100 | 0.80 | CACNA1D (0.33) | CACNA1DMDM2 | |
| SCHEMBL6680769 | 0.78 | SLC9A1 (0.34) | CACNA1DHCRTR1HCRTR2 | |
| SCHEMBL6678116 | 0.78 | — | — | |
| SCHEMBL6679649 | 0.77 | CACNA1D (0.35) | CACNA1DHCRTR1HCRTR2 | |
| SCHEMBL6639930 | 0.77 | KIF11 (0.32) | CACNA1D | |
| SCHEMBL6677411 | 0.75 | ATM (0.33) | CACNA1D | |
| SCHEMBL6677390 | 0.75 | MEN1 (0.31) | CACNA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |