Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 18/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6677019 | 0.99 | C5AR1 (0.59) | C5AR1LMNAMEN1POLBRAB9A | |
| SCHEMBL6675276 | 0.85 | ADRA2A (0.46) | C5AR1MAPT | |
| Hydrochloric Acid SCHEMBL6676250 | 0.84 | ADRA2A (0.48) | C5AR1 | |
| SCHEMBL6675023 | 0.82 | C5AR1 (0.58) | C5AR1LMNAMEN1POLBRAB9A | |
| SCHEMBL6680859 | 0.81 | PTGIR (0.51) | C5AR1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL6678424 | 0.81 | C5AR1 (0.54) | C5AR1MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL6676156 | 0.80 | PTGIR (0.50) | C5AR1LMNAMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6680957 | 0.80 | C5AR1 (0.53) | C5AR1MEN1KMT2AMAPT | |
| SCHEMBL6678175 | 0.79 | C5AR1 (0.48) | C5AR1LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL27479163 | 0.78 | C5AR1 (0.47) | C5AR1LMNAMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |