SCHEMBL6678264

SCHEMBL6678264

CCOc1cccc(P(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.52
TP53 P04637 2/20 0.52
LTA4H P09960 1/20 0.50
MAPK1 P28482 3/20 0.45
LMNA P02545 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
ALDH1A1 P00352 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
KDM4E B2RXH2 2/20 0.44
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
MAPT P10636 3/20 0.43
MEN1 O00255 1/20 0.43
RECQL P46063 1/20 0.43
KMT2A Q03164 1/20 0.43
RELA Q04206 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10881069 0.94 TP53 (0.57) CYP3A4TP53LTA4HMAPK1LMNA
SCHEMBL20873229 0.85 LTA4H (0.47) CYP3A4TP53LTA4HMAPK1LMNA
SCHEMBL15281165 0.85 TDP1 (0.48) CYP3A4LTA4HMAPK1LMNAL3MBTL1
SCHEMBL15281177 0.85 CYP3A4 (0.48) CYP3A4TDP1KDM4EGAA
SCHEMBL15281150 0.83 KCNA3 (0.50) CYP3A4TDP1ALDH1A1RECQL
SCHEMBL14769625 0.83 KCNA3 (0.56) CYP3A4LMNATDP1KDM4EMAPT
SCHEMBL6680067 0.82 LTA4H (0.61) CYP3A4TP53LTA4HL3MBTL1TDP1
SCHEMBL2154351 0.82 TP53 (0.49) CYP3A4TP53LTA4HMAPK1LMNA
SCHEMBL2154108 0.82 TP53 (0.49) CYP3A4TP53LTA4HMAPK1LMNA
SCHEMBL15281130 0.81 KCNA3 (0.54) CYP3A4TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004048463-A1 POLYMERIC COMPOSITIONS RAPIDLY HEATABLE UNDER ELECTROMAGNETIC IRRADIATION, THEIR USES AND PROCESSING METHODS PARODI FABRIZIO (IT) 2004-06-10 WO claimed
EP-3216796-B1 PHOSPHONIUM COMPOUND AND PRODUCTION METHOD THEREFOR UNIV TOHOKU (JP) 2020-08-19 EP disclosed
EP-3216796-A1 PHOSPHONIUM COMPOUND AND PRODUCTION METHOD THEREFOR Tohoku University (JP) 2017-09-13 EP disclosed
WO-2004048463-A1 POLYMERIC COMPOSITIONS RAPIDLY HEATABLE UNDER ELECTROMAGNETIC IRRADIATION, THEIR USES AND PROCESSING METHODS PARODI FABRIZIO (IT) 2004-06-10 WO disclosed