Hexadecylamine

Hexadecylamine

SCHEMBL6678352

CCCCCCCCCCCCCCCCN.Cc1ccc(S(=O)(=O)O)cc1.N.N

nearest known ligand 0.48

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Known targets — ChEMBL curated mechanism

ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hexadecylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 1/20 0.48
ALDH1A1 P00352 4/20 0.47
CYP2C9 P11712 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
CYP1A2 P05177 1/20 0.43
TSHR P16473 2/20 0.42
LMNA P02545 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
ALB P02768 1/20 0.42
DNM1 Q05193 6/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
EPHX1 P07099 1/20 0.42
S1PR3 Q99500 1/20 0.42
CA2 P00918 1/20 0.41
CNR2 P34972 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Decylamine SCHEMBL17289256 1.00 MCHR1 (0.48) MCHR1ALDH1A1CYP2C9L3MBTL1CYP1A2
SCHEMBL11786735 0.98 MCHR1 (0.49) MCHR1ALDH1A1CYP2C9L3MBTL1CYP1A2
SCHEMBL6910871 0.98 MCHR1 (0.49) MCHR1ALDH1A1CYP2C9L3MBTL1CYP1A2
Dodecylamine SCHEMBL28101896 0.98 MCHR1 (0.49) MCHR1ALDH1A1CYP2C9L3MBTL1CYP1A2
Octadecylamine SCHEMBL28750204 0.98 MCHR1 (0.49) MCHR1ALDH1A1CYP2C9L3MBTL1CYP1A2
Hexadecylamine SCHEMBL9058486 0.98 MCHR1 (0.49) MCHR1ALDH1A1CYP2C9L3MBTL1CYP1A2
Decylamine SCHEMBL29134163 0.98 MCHR1 (0.49) MCHR1ALDH1A1CYP2C9L3MBTL1CYP1A2
SCHEMBL27927799 0.97 MCHR1 (0.46) MCHR1ALDH1A1CYP2C9L3MBTL1CYP1A2
Butylamine SCHEMBL1934217 0.92 CYP2C9 (0.46) MCHR1ALDH1A1CYP2C9L3MBTL1CYP1A2
SCHEMBL8981419 0.92 CYP2C9 (0.48) ALDH1A1CYP2C9L3MBTL1CYP1A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711997-B1 Electrochemical surface analysis using deoxygenated gel electrolyte ROCKWELL INTERNATIONAL CORP (US) 2004-11-10 EP claimed
US-6214210-B1 QUANTITATIVE ANALYSIS OF SURFACE OXIDES ROCKWELL TECHNOLOGIES, LLC 2001-04-10 US claimed
EP-0711997-A2 Electrochemical surface analysis using deoxygenated gel electrolyte ROCKWELL INTERNATIONAL CORPORATION (US) 1996-05-15 EP claimed
EP-0711997-B1 Electrochemical surface analysis using deoxygenated gel electrolyte ROCKWELL INTERNATIONAL CORP (US) 2004-11-10 EP disclosed
US-6214210-B1 QUANTITATIVE ANALYSIS OF SURFACE OXIDES ROCKWELL TECHNOLOGIES, LLC 2001-04-10 US disclosed
EP-0711997-A2 Electrochemical surface analysis using deoxygenated gel electrolyte ROCKWELL INTERNATIONAL CORPORATION (US) 1996-05-15 EP disclosed