Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680589 | 0.87 | PDPK1 (0.53) | POLBKMT2ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6675046 | 0.85 | PDPK1 (0.55) | POLBKMT2ACYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL6678458 | 0.84 | PTGS1 (0.43) | POLBKMT2ACYP2C9CYP2C19LMNA | |
| SCHEMBL6678494 | 0.84 | KMT2A (0.48) | POLBKMT2ALMNASMN1; SMN2CYP19A1 | |
| SCHEMBL10033931 | 0.82 | KMT2A (0.54) | POLBKMT2ACYP2C9CYP2C19LMNA | |
| SCHEMBL6676805 | 0.82 | NPC1 (0.55) | KMT2ACYP2C9CYP2C19LMNASMN1; SMN2 | |
| SCHEMBL10033957 | 0.81 | ALDH1A1 (0.53) | KMT2ACYP2C9CYP2C19LMNASMN1; SMN2 | |
| SCHEMBL6676787 | 0.79 | NPC1 (0.50) | POLBKMT2ACYP2C9CYP2C19LMNA | |
| SCHEMBL6673825 | 0.75 | TSHR (0.55) | KMT2ACYP2C9CYP2C19LMNASMN1; SMN2 | |
| SCHEMBL22014067 | 0.73 | TSHR (0.56) | KMT2ACYP2C9CYP2C19LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204636-A1 | 3-OXOPROPANE-1-SULPHONIC ACIDS AND SULPHONATES | DSM N.V. (NL) | 2002-05-15 | — | — | EP | claimed |
| WO-2001014327-A1 | 3-OXOPROPANE-1-SULPHONIC ACIDS AND SULPHONATES | DSM N.V. (NL) | 2001-03-01 | — | — | WO | claimed |
| EP-1204636-B1 | 3-OXOPROPANE-1-SULPHONIC ACIDS AND SULPHONATES | DSM IP ASSETS BV (NL) | 2004-10-27 | — | — | EP | disclosed |
| US-6639103-B1 | Enantiomerically enriched forms; resolving amino functiona-lized enantiomers | DSM N.V. (NL) | 2003-10-28 | — | — | US | disclosed |