Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.56 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | BCL9 | O00512 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683078 | 0.83 | TAAR1 (0.41) | MGLLMAPTRAB9APKMGAA | |
| SCHEMBL6682458 | 0.80 | KMT2A (0.58) | MGLLFAAHTRPV1ALDH1A1MAPT | |
| SCHEMBL18703462 | 0.79 | MGLL (0.78) | MGLLFAAHTRPV1MAPTRAB9A | |
| SCHEMBL18375247 | 0.79 | MGLL (0.58) | MGLLFAAHTRPV1ALDH1A1MAPT | |
| SCHEMBL2114516 | 0.77 | HTR2A (0.52) | MGLLALDH1A1MAPTBCL9CTNNB1 | |
| SCHEMBL19412173 | 0.77 | MGLL (0.84) | MGLLFAAHTRPV1ALDH1A1BCL9 | |
| SCHEMBL6487654 | 0.76 | MAPT (0.46) | ALDH1A1MAPTRAB9AGAAKMT2A | |
| SCHEMBL11668314 | 0.76 | MGLL (0.86) | MGLLFAAHTRPV1ALDH1A1BCL9 | |
| SCHEMBL14565135 | 0.76 | MGLL (0.86) | MGLLFAAHTRPV1ALDH1A1BCL9 | |
| SCHEMBL28915067 | 0.75 | TAAR1 (0.67) | MGLLFAAHTRPV1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |