Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.58 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.58 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.58 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.58 |
| ▸ | ACE | P12821 | 8/20 | 0.55 |
| ▸ | XPNPEP2 | O43895 | 2/20 | 0.55 |
| ▸ | REN | P00797 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PEPD | P12955 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | THPO | P40225 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679094 | 1.00 | DPP4 (0.58) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL30729290 | 0.94 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL30567640 | 0.94 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3052901 | 0.94 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL3052903 | 0.94 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL11591710 | 0.94 | DPP4 (0.63) | DPP4DPP8DPP9DPP7ACE | |
| Trifluoroacetic Acid SCHEMBL29802195 | 0.87 | DPP4 (0.55) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL30069057 | 0.87 | DPP4 (0.50) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL15371247 | 0.86 | ACE (0.57) | DPP4DPP8DPP9DPP7ACE | |
| SCHEMBL31514391 | 0.86 | ACE (0.54) | DPP4DPP8DPP9DPP7ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118047839-A | Blood glucose reducing functional polypeptide and application thereof | 华南理工大学 | 2024-05-17 | — | — | CN | claimed |
| US-12622975-B2 | Peptide-conjugated prodrugs | BRANDEIS UNIVERSITY (US) | 2026-05-12 | — | — | US | disclosed |
| CN-119220557-A | Rice nitrogen efficient utilization gene OsNAC15, protein coded by same and application thereof | 东北农业大学 | 2024-12-31 | — | — | CN | disclosed |
| US-20220387610-A1 | PEPTIDE-CONJUGATED PRODRUGS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-12-08 | — | — | US | disclosed |
| US-11484564-B2 | Adhesion prevention material | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2022-11-01 | — | — | US | disclosed |
| CN-114656548-A | Antihypertensive peptide, and preparation method and application thereof | 练文飞 | 2022-06-24 | — | — | CN | disclosed |
| CN-110669122-B | Preparation method of zein anti-inflammatory polypeptide | 江苏大学 | 2022-06-21 | — | — | CN | disclosed |
| EP-1476746-A2 | METHOD FOR DISCOVERING PHARMACOLOGICALLY ACTIVE SUBSTANCES | Paion GmbH (DE) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003071268-A2 | METHOD FOR DISCOVERING PHARMACOLOGICALLY ACTIVE SUBSTANCES | PAION GMBH (DE) | 2003-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12622975-B2 | Peptide-conjugated prodrugs | PEPD, PAM, VIP | DPP4 43/4885DPP8 41/4885DPP9 59/4885 |
| US-20220387610-A1 | PEPTIDE-CONJUGATED PRODRUGS | VIP, DNPEP, PEPD | DPP4 73/4885DPP8 40/4885DPP9 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.