Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6675302 | 0.99 | ALDH1A1 (0.44) | ALDH1A1ALOX5MAPTMEN1KMT2A | |
| SCHEMBL6678287 | 0.88 | TDP1 (0.42) | ALDH1A1MAPTMEN1KMT2APOLB | |
| Hydrochloric Acid SCHEMBL6680098 | 0.87 | TDP1 (0.41) | ALDH1A1MAPTMEN1KMT2APOLB | |
| SCHEMBL6678424 | 0.82 | C5AR1 (0.54) | MAPTMEN1KMT2A | |
| SCHEMBL6677745 | 0.81 | C5AR1 (0.51) | — | |
| Hydrochloric Acid SCHEMBL6680957 | 0.81 | C5AR1 (0.53) | MAPTMEN1KMT2A | |
| SCHEMBL7246442 | 0.81 | ALDH1A1 (0.44) | ALDH1A1ALOX5MAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6680958 | 0.80 | C5AR1 (0.50) | — | |
| SCHEMBL6679456 | 0.80 | SMN1; SMN2 (0.37) | ALDH1A1MAPTMAPK1GRIN2DGRIN3B | |
| SCHEMBL6680859 | 0.79 | PTGIR (0.51) | ALDH1A1MAPTMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |