Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 16/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678424 | 0.82 | C5AR1 (0.54) | C5AR1MEN1MAPTKMT2ACTSV | |
| SCHEMBL6686056 | 0.82 | C5AR1 (0.54) | C5AR1MEN1MAPTKMT2ACTSV | |
| SCHEMBL6679217 | 0.82 | LTA4H (0.47) | C5AR1LTA4HMEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL6680957 | 0.81 | C5AR1 (0.53) | C5AR1MEN1MAPTKMT2ACTSV | |
| SCHEMBL6678655 | 0.76 | C5AR1 (0.48) | C5AR1MEN1MAPTKMT2ACTSV | |
| SCHEMBL6681429 | 0.76 | C5AR1 (0.47) | C5AR1MEN1MAPTKMT2A | |
| SCHEMBL6678287 | 0.70 | TDP1 (0.42) | C5AR1MEN1MAPTKMT2A | |
| SCHEMBL6675007 | 0.70 | GRIN2D (0.49) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6680098 | 0.70 | TDP1 (0.41) | MEN1MAPTKMT2A | |
| SCHEMBL11403630 | 0.69 | KMT2A (0.52) | MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |
| US-6534546-B1 | Guanidine- or isothioureido-N-derived anilines; brain, nervous system, and neurodegenerative disorders | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-03-18 | — | — | US | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |