SCHEMBL6679401

SCHEMBL6679401

CC[N+](CC)C1CC(C)(C)Oc2c(C)c(C)c(O)c(C)c21

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
ALOX5 P09917 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6681011 0.79 ALOX5 (0.36) ALOX5
SCHEMBL5839586 0.78 PTGS1 (0.36) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL5267073 0.74 MEN1 (0.39) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL5268517 0.68 PTGS1 (0.32) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL6678052 0.67 PTGS1 (0.33) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL5839654 0.67 PTGS1 (0.37) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL7050816 0.66 PTGS1 (0.32) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL5839402 0.65 CYP3A4 (0.34) PTGS1PTGS2CYP1A2CYP3A4TSHR
SCHEMBL8536285 0.65 ALOX5 (0.37) PTGS1PTGS2CYP1A2CYP3A4TSHR
Alcohol SCHEMBL8867372 0.64 ALOX5 (0.36) PTGS1PTGS2CYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1301504-B1 BIFUNCTIONAL AGENTS POSSESSING ANTIOXIDANT AND ANTIARRHYTHMIC ACTIVITY UNI PHARMA KLEON TSETIS PHARMACEUTICAL LAB SA (GR) 2004-11-03 EP claimed