SCHEMBL667942

SCHEMBL667942

COc1ccc(P(c2ccc(OC)cc2OC)c2ccc(OC)cc2OC)c(OC)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.60
CA1 P00915 2/20 0.60
CA2 P00918 2/20 0.60
CA7 P43166 2/20 0.60
CA9 Q16790 2/20 0.60
CA14 Q9ULX7 2/20 0.60
CYP1A1 P04798 7/20 0.52
CYP1A2 P05177 7/20 0.52
CYP1B1 Q16678 7/20 0.52
ALDH1A1 P00352 5/20 0.52
CYP3A4 P08684 2/20 0.52
MAPT P10636 3/20 0.50
HPGD P15428 2/20 0.50
RAD52 P43351 1/20 0.50
NPC1 O15118 1/20 0.47
GAA P10253 1/20 0.47
CYP2E1 P05181 1/20 0.47
CYP2C8 P10632 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2A6 P11509 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31240957 1.00 CA12 (0.60) CA12CA1CA2CA7CA9
SCHEMBL1834676 0.85 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL9838572 0.84 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL18855065 0.84 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL5154770 0.83 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL2884396 0.83 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL29509911 0.83 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL17377389 0.83 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL8029752 0.83 CA12 (0.56) CA12CA1CA2CA7CA9
SCHEMBL9715789 0.82 CA12 (0.60) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2321244-B1 IMPROVED PROCESS FOR TELOMERIZATION OF BUTADIENE DOW GLOBAL TECHNOLOGIES LLC (US) 2016-12-21 EP claimed
US-8558030-B2 Process for telomerization of butadiene DOW GLOBAL TECHNOLOGIES LLC (US) 2013-10-15 US claimed
US-20110137086-A1 PROCESS FOR TELOMERIZATION OF BUTADIENE Dow Global Technologies LLC (Formerly known as Dow Global Technologies Inc.) (US) 2011-06-09 US claimed
EP-2321244-A2 AN IMPROVED PROCESS FOR TELOMERIZATION OF BUTADIENE Dow Global Technologies LLC (US) 2011-05-18 EP claimed
WO-2010019360-A2 AN IMPROVED PROCESS FOR TELOMERIZATION OF BUTADIENE DOW GLOBAL TECHNOLOGIES INC. (US) 2010-02-18 WO claimed
WO-2005123662-A1 MODIFIED HECK REACTION JANSSEN PHARMACEUTICA N.V. (BE) 2005-12-29 WO claimed
US-20040260039-A1 Process for producing organic compound epoxy resin composition, cured article obtained from the epoxy resin, and semiconductor device obtained with epoxy resin MITSUI CHEMICALS, INC. (JP) 2004-12-23 US claimed
US-20020137820-A1 Phosphorus compounds SANDOZ LTD. (CH) 2002-09-26 US claimed
CN-112694599-A Phenoxy resin, method for producing same, resin composition thereof, and cured product 日铁化学材料株式会社 2021-04-23 CN disclosed
EP-2321244-B1 IMPROVED PROCESS FOR TELOMERIZATION OF BUTADIENE DOW GLOBAL TECHNOLOGIES LLC (US) 2016-12-21 EP disclosed
US-8912346-B2 Palladium phosphine complexes for the telomerization of butadiene DOW GLOBAL TECHNOLOGIES LLC (US) 2014-12-16 US disclosed
CN-102666443-B Separation of components from a multi-component hydrocarbon stream which includes ethylene SASOL TECH PTY LTD 2014-09-03 CN disclosed
US-8779164-B2 Phosphine-based catalysts useful for the telomerization of butadiene DOW GLOBAL TECHNOLOGIES LLC (US) 2014-07-15 US disclosed
US-8558030-B2 Process for telomerization of butadiene DOW GLOBAL TECHNOLOGIES LLC (US) 2013-10-15 US disclosed
US-5700899-A Curable silicone compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-12-23 US disclosed
US-5488079-A HEAT AND LIGHT STABILIZERS FOR OLEFINS USING PHOSPHINES SANDOZ LTD. (CH) 1996-01-30 US disclosed
EP-0687718-A1 Curable silicone compositions SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-12-20 EP disclosed
EP-0286196-B1 PREPARATION OF SUBSTITUTED DIARYL PHOSPHIDES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1992-03-25 EP disclosed
EP-0364046-A2 Preparation of tetraaryldiphosphines SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-04-18 EP disclosed
EP-0286196-A2 Preparation of substituted diaryl phosphides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1988-10-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110137086-A1 PROCESS FOR TELOMERIZATION OF BUTADIENE HRH3, HRH4, TELO2 CA12 4195/4885CA1 4615/4885CA2 3509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.